OPAT means Outpatient parenteral ≠antimicrobial therapy


Outpatient parenteral antimicrobial therapy (OPAT) is the administration of at least 2 consecutive days of parenteral (usually intravenous) antimicrobial therapy without an overnight hospital stay. It is reserved for those patients with infection in whom parenteral antimicrobial therapy is required but who otherwise could be safely managed without hospital admission.

An OPAT service should be carefully designed and delivered to ensure safe and effective patient care. As such it is essential that a patientís other social and healthcare needs can be managed safely in the home environment.

An aim of OPAT ist

Allow earlier hospital discharge for selected patients with deep seated infections requiring parenteral therapy e.g. osteomyelitis, endocarditis and device-related infections. [BASC]


There are two types of treatment:

- Patients who need antibiotics once a day

- Patients who need continuous administration of antibiotics


For the second group an  elastomeric pump will be used.



amenable infections

suitable antibiotics

elastomeric pump

Easypump II


close patient follow up among patients receiving outpateint parenteral antimicrobial therapy LINK

opat in switzerland: single center experience of a model to treat complicated infections LINK

updated good pracitice recommendations for outpatient parenteral antimicroboal therapy (OPAT) in adults and children in the UK LINK

outpatient parenteral antimicrobial therapy: updated recommendations from the UK LINK


service development of a nurse led community based picc insertion service LINK

quality of outpatient parenteral antimicrobial therapy (OPAT) care from the patientís perspective: a qualitative study (2018) LINK